Selected Publications

  • Senataxin deficiency disrupts proteostasis through nucleolar ncRNA-driven protein aggregation

    July 2024

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  • Regulation of transcription patterns, poly(ADP-ribose), and RNA-DNA hybrids by the ATM protein kinase

    March 2024

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  • Genome-wide analysis of DNA-PK-bound MRN cleavage products supports a sequential model of DSB repair pathway choice

    September 2023

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  • Poly-ADP-ribosylation drives loss of protein homeostasis in ATM and Mre11 deficiency

    April 2021

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  • Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

    July 2020

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  • DNA-dependent protein kinase promotes DNA end processing by MRN and CtIP

    January 2020

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  • Sae2/CtIP prevents R-loop accumulation in eukaryotic cells

    December 2018

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  • ATM directs DNA damage responses and proteostasis via genetically separable pathways

    January 2018

    Full Text

  • Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair

    September 2017

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